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Article

Neutralization of SARS-CoV-2 Variants of Concern Harboring Q677H.

mBio - 26 Oct 2021

Zeng Cong, Evans John P, Faraone Julia N, Qu Panke, Zheng Yi-Min, Saif Linda, Oltz Eugene M, Lozanski Gerard, Gumina Richard J, Liu Shan-Lu

Abstract excerpt

The sensitivity of SARS-CoV-2 variants of concern (VOCs) to neutralizing antibodies has largely been studied in the context of key receptor binding domain (RBD) mutations, including E484K and N501Y. Little is known about the epistatic effects of combined SARS-CoV-2 spike mutations. We now investigate the neutralization sensitivity of variants containing the non-RBD mutation Q677H, including B.1.525 (Nigerian...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34607452
DOI: 10.1128/mBio.02510-21
PMCID: PMC8527387

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