Article
Associations between tumor mutations in cfDNA and survival in non-small cell lung cancer.
Cancer treatment and research communications - 1 Jan 2021
Ottestad Anine Larsen, Dai Hong Yan, Halvorsen Tarje Onsøien, Emdal Elisabeth Fritzke, Wahl Sissel Gyrid Freim, Grønberg Bjørn Henning
Abstract excerpt
INTRODUCTION: Studies have indicated that detection of mutated KRAS or EGFR in circulating tumor DNA (ctDNA) from pre-treatment plasma samples is a negative prognostic factor for non-small cell lung cancer (NSCLC) patients. This study aims to investigate whether this is the case also for NSCLC patients with other tumor mutations. METHODS: Tumor tissue DNA from 107 NSCLC patients was sequenced and corresponding...
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