Article
The prognostic value of KRAS mutated plasma DNA in advanced non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) - 1 Mar 2013
Nygaard Anneli Dowler, Garm Spindler Karen-Lise, Pallisgaard Niels, Andersen Rikke Fredslund, Jakobsen Anders
Abstract excerpt
BACKGROUND: Lung cancer is one of the most common malignant diseases worldwide and associated with considerable morbidity and mortality. New agents targeting the epidermal growth factor system are emerging, but only a subgroup of the patients will benefit from the therapy. Cell free DNA (cfDNA) in the blood allows for tumour specific analyses, including KRAS-mutations, and the aim of the study was to investigate...
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