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Whole Genome Analysis of Human Rotaviruses Reveals Single Gene Reassortant Rotavirus Strains in Zambia.

Viruses - 18 Sept 2021

Maringa Wairimu M, Simwaka Julia, Mwangi Peter N, Mpabalwani Evans M, Mwenda Jason M, Mphahlele M Jeffrey, Seheri Mapaseka L, Nyaga Martin M

Abstract excerpt

Rotarix® vaccine was implemented nationwide in Zambia in 2013. In this study, four unusual strains collected in the post-vaccine period were subjected to whole genome sequencing and analysis. The four strains possessed atypical genotype constellations, with at least one reassortant genome segment within the constellation. One of the strains (UFS-NGS-MRC-DPRU4749) was genetically and phylogenetically distinct in...

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Source

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Identifiers

PMID: 34578453
DOI: 10.3390/v13091872
PMCID: PMC8472975

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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