Article
Association of a GATA Binding Protein 4 Polymorphism with the Risk of Hypospadias in the Chinese Children.
Urologia internationalis - 1 Jan 2021
Chen Jiawei, Cui Xinhai, Li Aiwu, Li Guowei, Sun Fengyin
Abstract excerpt
PURPOSE: GATA binding protein 4 (GATA4) has been implicated in the etiology of congenital malformation of the urogenital system. The present study investigated the influence of GATA4 polymorphisms on susceptibility to hypospadias. METHODS: We genotyped 4 potentially functional polymorphisms (rs12458, rs12825, rs884662, and rs904018) in GATA4 in the hospital-based case-control study including 410 child patients...
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