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Article

Emerging SARS-CoV-2 variants follow a historical pattern recorded in outgroups infecting non-human hosts.

Communications biology - 22 Sept 2021

Katoh Kazutaka, Standley Daron M

Abstract excerpt

The ability to predict emerging variants of SARS-CoV-2 would be of enormous value, as it would enable proactive design of vaccines in advance of such emergence. We estimated diversity of each site on a multiple sequence alignment (MSA) of the Spike (S) proteins from close relatives of SARS-CoV-2 that infected bat and pangolin before the pandemic. Then we compared the locations of high diversity sites in this MSA...

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Identifiers

PMID: 34552191
DOI: 10.1038/s42003-021-02663-4
PMCID: PMC8458489

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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