Article
Deep GONet: self-explainable deep neural network based on Gene Ontology for phenotype prediction from gene expression data.
BMC bioinformatics - 22 Sept 2021
Bourgeais Victoria, Zehraoui Farida, Ben Hamdoune Mohamed, Hanczar Blaise
Abstract excerpt
BACKGROUND: With the rapid advancement of genomic sequencing techniques, massive production of gene expression data is becoming possible, which prompts the development of precision medicine. Deep learning is a promising approach for phenotype prediction (clinical diagnosis, prognosis, and drug response) based on gene expression profile. Existing deep learning models are usually considered as black-boxes that...
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