Article
Evaluation of the risk of metachronous multiple squamous cell carcinoma of the head and neck after transoral surgery based on the genetic polymorphisms of alcohol dehydrogenase 1B and aldehyde dehydrogenase 2.
Carcinogenesis - 26 Oct 2021
Inoue Masaki, Shimizu Yuichi, Taniguchi Masanobu, Kimura Yuki, Furuhashi Hiroto, Dobashi Akira, Ikeya Takashi, Goda Kenichi, Kato Masayuki, Kato Mototsugu, Sakamoto Naoya, Watanabe Akihito
Abstract excerpt
Patients with superficial head and neck squamous cell carcinoma (HNSCC) can be completely treated by techniques of transoral surgery (TOS). The aim of this study was to evaluate the risk of metachronous multiple HNSCC arising after TOS based on alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2). We registered patients who underwent TOS for superficial HNSCC. Buccal cell samples were obtained by...
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