Article
Evaluation of the association of the Renalase rs10887800 polymorphism with the risk of preeclampsia in Brazilian women.
Pregnancy hypertension - 1 Mar 2022
de Freitas Moura Mara Suellem, Linhares José Juvenal, Noronha Emmanuelle Coelho, de Pina Fernandes Wanneida Christina, Simiano Tavares Kaio César, Marcelo Antunes André Saraiva Leão, Benevides Samara Casemiro, Barbalho Silva Anderson Weiny
Abstract excerpt
Despite advances in obstetric medicine, the pathogenesis of preeclampsia (PE) remains poorly understood. It has been suggested that PE results from a state of sympathetic hyperactivity with circulating catecholamines increased in this condition. A new enzyme, called Renalase, has recently been identified exhibiting activity on the metabolism of catecholamine and blood pressure reduction when administered in vivo....
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