Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

20 Sept 2021

Abstract excerpt

Emerging variants of SARS-CoV-2 have been shown to rapidly replace original circulating strains in humans soon after they emerged. There is a lack of experimental evidence to explain how these natural occurring variants spread more efficiently than existing strains of SARS-CoV-2 in transmission. We found that the Alpha variant (B.1.1.7) increased competitive fitness over earlier parental D614G lineages in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 epidemiological studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral Infections and Outbreaks Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34545191
DOI: 10.1038/s42003-021-02640-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamstersPMID 34545191Read ↗

Low dose inocula of SARS-CoV-2 B.1.1.7 variant initiate more robust infections in the upper respiratory tract of hamsters than earlier D614G variantsSemantic proximity Read ↗

Increased pathogenicity and aerosol transmission for one SARS-CoV-2 B.1.617.2 Delta variant over the wild-type strain in hamstersSemantic proximity Read ↗

Prior aerosol infection with lineage A SARS-CoV-2 variant protects hamsters from disease, but not reinfection with B.1.351 SARS-CoV-2 variantSemantic proximity Read ↗

SARS-CoV-2 B.1.1.7 infection of Syrian hamster does not cause more severe disease and is protected by naturally acquired immunitySemantic proximity Read ↗

Prior aerosol infection with lineage A SARS-CoV-2 variant protects hamsters from disease, but not reinfection with B.1.351 SARS-CoV-2 variantSemantic proximity Read ↗

SARS-CoV-2 Delta Variant Pathogenesis and Host Response in Syrian HamstersSemantic proximity Read ↗

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication <i>ex vivo</i> and Earlier Transmission <i>in vivo</i>Semantic proximity Read ↗

Enhanced fitness of SARS-CoV-2 variant of concern B.1.1.7, but not B.1.351, in animal modelsSemantic proximity Read ↗

SARS-CoV-2 spike D614G variant exhibits highly efficient replication and transmission in hamstersSemantic proximity Read ↗

SARS CoV-2 variant B.1.617.1 is highly pathogenic in hamsters than B.1 variantSemantic proximity Read ↗

SARS-CoV-2 Delta variant pathogenesis and host response in Syrian hamstersSemantic proximity Read ↗

Comparison of the pathogenicity and virus shedding of SARS CoV-2 VOC 202012/01 and D614G variant in hamster modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.