Article
Association between the FTO rs9939609 single nucleotide polymorphism and dietary adherence during a 2-year caloric restriction intervention: Exploratory analyses from CALERIE™ phase 2.
Experimental gerontology - 1 Nov 2021
Dorling James L, Belsky Daniel W, Racette Susan B, Das Sai Krupa, Ravussin Eric, Redman Leanne M, Höchsmann Christoph, Huffman Kim M, Kraus William E, Kobor Michael S, MacIsaac Julia L, Lin David T S, Corcoran David L, Martin Corby K
Abstract excerpt
Caloric restriction (CR) improves markers of aging in humans; but it is not known if the fat mass and obesity-associated gene (FTO) rs9939609 single nucleotide polymorphism (SNP), which is associated with appetite and energy intake, influences adherence to prolonged CR. Utilizing data from the two-year Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy (CALERIE™) phase 2 randomized...
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