Article
HIST1H2BN induced cell proliferation and EMT phenotype in prostate cancer via NF-κB signal pathway.
Genes & genomics - 1 Nov 2021
Zhang Juan, Chang Yuhan, Xia Haiyan, Xu Luwei, Wei Xiaowei
Abstract excerpt
BACKGROUND: The potential role of HIST1H2BN in prostate cancer remains unclear. OBJECTIVE: To evaluate the carcinogenic role of HIST1H2BN in prostate cancer. METHODS: The expression of HIST1H2BN in prostate cancer was analyzed using TCGA database and clinical samples. The roles and mechanisms of HIST1H2BN were investigated in DU145 and PC3 cells. RESULTS: HIST1H2BN was significantly upregulated in prostate...
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