Article
The emergence and ongoing convergent evolution of the SARS-CoV-2 N501Y lineages.
Cell - 30 Sept 2021
Martin Darren P, Weaver Steven, Tegally Houriiyah, San James Emmanuel, Shank Stephen D, Wilkinson Eduan, Lucaci Alexander G, Giandhari Jennifer, Naidoo Sureshnee, Pillay Yeshnee, Singh Lavanya, Lessells Richard J, Gupta Ravindra K, Wertheim Joel O, Nekturenko Anton, Murrell Ben, Harkins Gordon W, Lemey Philippe, MacLean Oscar A, Robertson David L, de Oliveira Tulio, Kosakovsky Pond Sergei L
Abstract excerpt
The independent emergence late in 2020 of the B.1.1.7, B.1.351, and P.1 lineages of SARS-CoV-2 prompted renewed concerns about the evolutionary capacity of this virus to overcome public health interventions and rising population immunity. Here, by examining patterns of synonymous and non-synonymous mutations that have accumulated in SARS-CoV-2 genomes since the pandemic began, we find that the emergence of these...
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