Article
Contribution of single mutations to selected SARS-CoV-2 emerging variants spike antigenicity.
Virology - 1 Nov 2021
Gong Shang Yu, Chatterjee Debashree, Richard Jonathan, Prévost Jérémie, Tauzin Alexandra, Gasser Romain, Bo Yuxia, Vézina Dani, Goyette Guillaume, Gendron-Lepage Gabrielle, Medjahed Halima, Roger Michel, Côté Marceline, Finzi Andrés
Abstract excerpt
Towards the end of 2020, multiple variants of concern (VOCs) and variants of interest (VOIs) have arisen from the original SARS-CoV-2 Wuhan-Hu-1 strain. Mutations in the Spike protein are highly scrutinized for their impact on transmissibility, pathogenesis and vaccine efficacy. Here, we contribute to the growing body of literature on emerging variants by evaluating the impact of single mutations on the overall...
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