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The Intertwining of Autophagy and the Ubiquitin Proteasome System in Podocyte (Patho)Physiology

15 Sept 2021

Abstract excerpt

Protein homeostasis strongly depends on the targeted and selective removal of unneeded or flawed proteins, of protein aggregates, and of damaged or excess organelles by the two main intracellular degradative systems, namely the ubiquitin proteasomal system (UPS) and the autophagosomal lysosomal system. Despite representing completely distinct mechanisms of degradation, which underlie differing regulatory...

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PMID: 34523304
DOI: 10.33594/000000432

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