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Article

The targeted podocyte.

The Journal of clinical investigation - 1 Jun 2011

Fogo Agnes B

Abstract excerpt

The podocyte plays a key role both in maintenance of the glomerular filtration barrier and in glomerular structural integrity. Podocyte injury and loss contribute to proteinuria and progressive sclerosis. Inhibitors of mammalian target of rapamycin (mTOR) have variably decreased or caused proteinuria and sclerosis in human disease and experimental settings. In this issue of the JCI, two interesting studies of...

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Share to Adaptor Proteins, Signal Transducing
Share to Diabetic Nephropathies
Share to Kidney Glomerulus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mechanistic Target of Rapamycin Complex 1

Share to Multiprotein Complexes

Share to Podocytes

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Share to TOR Serine-Threonine Kinases

Source

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Identifiers

PMID: 21606599
DOI: 10.1172/JCI57935
PMCID: PMC3104780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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