9p24.1 alterations and programmed cell death 1 ligand 1 expression in early stage unfavourable classical Hodgkin lymphoma: an analysis from the German Hodgkin Study Group NIVAHL trial.

doi:10.1111/bjh.17793

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Article

9p24.1 alterations and programmed cell death 1 ligand 1 expression in early stage unfavourable classical Hodgkin lymphoma: an analysis from the German Hodgkin Study Group NIVAHL trial.

British journal of haematology - 1 Jan 2022

Gerhard-Hartmann Elena, Goergen Helen, Bröckelmann Paul J, Mottok Anja, Steinmüller Tabea, Grund Johanna, Zamò Alberto, Ben-Neriah Susana, Sasse Stephanie, Borchmann Sven, Fuchs Michael, Borchmann Peter, Reinke Sarah, Engert Andreas, Veldman Johanna, Diepstra Arjan, Klapper Wolfram, Rosenwald Andreas

Abstract excerpt

High programmed cell death 1 ligand 1 (PD-L1) protein expression and copy number alterations (CNAs) of the corresponding genomic locus 9p24.1 in Hodgkin- and Reed-Sternberg cells (HRSC) have been shown to be associated with favourable response to anti-PD-1 checkpoint inhibition in relapsed/refractory (r/r) classical Hodgkin lymphoma (cHL). In the present study, we investigated baseline 9p24.1 status as well as...

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PMID: 34520052
DOI: 10.1111/bjh.17793

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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