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Article

Rosai-Dorfman disease in the central nervous system with two isolated lesions originated from a single clone: a case report.

BMC neurology - 13 Sept 2021

Jin Huawei, Yu Zhenhua, Tian Tian, Shen Guoping, Chen Weian, Fan Miao, He Qun, Xu Fei, Liu Dawei

Abstract excerpt

BACKGROUND: Rosai-Dorfman disease (RDD) is a rare, benign, idiopathic non-Langerhans cell histiocytosis. Cases of RDD in the CNS are extremely rare but lethal. RDD is thought to represent a reactive process. Recent studies proposed a subset of RDD cases that had a clonal nature. However, its clone origin is poorly understood. CASE PRESENTATION: We present a rare case of RDD in the CNS with two isolated lesions....

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PMID: 34517832
DOI: 10.1186/s12883-021-02379-2
PMCID: PMC8436543

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