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Article

Role of long non-coding RNAs in Down syndrome patients: a transcriptome analysis study.

Human cell - 1 Nov 2021

Salemi Michele, Cannarella Rossella, Marchese Giovanna, Salluzzo Maria Grazia, Ravo Maria, Barone Concetta, Giudice Mariangela Lo, Calogero Aldo E, Romano Corrado

Abstract excerpt

Down syndrome (DS) is defined by the presence of a third copy of chromosome 21. Several comorbidities can be found in these patients, such as intellectual disability (ID), muscle weakness, hypotonia, congenital heart disease, and autoimmune diseases. The molecular mechanisms playing a role in the development of such comorbidities are still unclear. The regulation and expression of genes that map to chromosome 21...

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Share to Chromosomes, Human, Pair 21
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34510387
DOI: 10.1007/s13577-021-00602-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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