Article
Influence of the rs6736 Polymorphism on Ischemic Stroke Susceptibility in Han Chinese Individuals via the Disruption of miR-7-1 Binding to the C14orf119 Gene.
Journal of molecular neuroscience : MN - 1 Mar 2022
Guo Xiaojing, Zhu Lulu, Zhao Xinyi, Wu Xulong, Yang Jialei, Huang Jiao, Gu Lian, Su Li
Abstract excerpt
This study investigates the association between the C14orf119 gene rs6736 polymorphism and ischemic stroke (IS) susceptibility, and explores the influence of the rs6736 polymorphism on the binding between miR-7-1 and the C14orf119 gene. mRNA expression levels were determined in 45 IS patients and 45 matched controls via real-time quantitative PCR. A total of 774 IS patients and 793 matched controls were recruited...
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