Article

Insights on Prevalence of Hereditary Aortic Thoracic Disease and Impact on Family Screening in Routine Clinical Cardiothoracic Surgery Care

2026-08-17

Abstract excerpt

<h4>Objective: </h4> Heritable thoracic aortic disease (HTAD) is an important cause of thoracic aortic aneurysm and dissection, yet remains underdiagnosed. We aimed to summarize the prevalence of syndromic and non-syndromic HTAD, describe variants of uncertain significance (VUS), and evaluate the impact of family screening in a contemporary cardiothoracic surgical cohort. <h4>Methods:</h4> Between 2018 and 2026, 1...

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Literature Corpus work: 3541b610-a2b0-5f44-94ce-d8a3df300d2c
DOI: 10.20944/preprints202608.1061.v1

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