The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.

doi:10.1093/ecco-jcc/jjab157

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Article

The Effect of Phenotype and Genotype on the Plasma Proteome in Patients with Inflammatory Bowel Disease.

Journal of Crohn's & colitis - 14 Mar 2022

Bourgonje Arno R, Hu Shixian, Spekhorst Lieke M, Zhernakova Daria V, Vich Vila Arnau, Li Yanni, Voskuil Michiel D, van Berkel Lisette A, Bley Folly Brenda, Charrout Mohammed, Mahfouz Ahmed, Reinders Marcel J T, van Heck Julia I P, Joosten Leo A B, Visschedijk Marijn C, van Dullemen Hendrik M, Faber Klaas Nico, Samsom Janneke N, Festen Eleonora A M, Dijkstra Gerard, Weersma Rinse K

Abstract excerpt

BACKGROUND AND AIMS: Protein profiling in patients with inflammatory bowel diseases [IBD] for diagnostic and therapeutic purposes is underexplored. This study analysed the association between phenotype, genotype, and the plasma proteome in IBD. METHODS: A total of 92 inflammation-related proteins were quantified in plasma of 1028 patients with IBD (567 Crohn's disease [CD]; 461 ulcerative colitis [UC]) and 148...

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Identifiers

PMID: 34491321
DOI: 10.1093/ecco-jcc/jjab157
PMCID: PMC8919819

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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