Article
Testing the association between tobacco smoking, alcohol consumption, and risk of periodontitis: A Mendelian randomization study.
Journal of clinical periodontology - 1 Nov 2021
Baumeister Sebastian-Edgar, Freuer Dennis, Nolde Michael, Kocher Thomas, Baurecht Hansjörg, Khazaei Yeganeh, Ehmke Benjamin, Holtfreter Birte
Abstract excerpt
AIM: To investigate the associations of tobacco smoking and alcohol consumption with periodontitis using Mendelian randomization (MR) analysis. MATERIALS AND METHODS: We used 17 single nucleotide polymorphisms (SNPs) as instrumental variables (IVs) for the number of cigarettes per day from a genome-wide association study (GWAS) of 337,334 individuals, 109 SNPs for a lifetime smoking index from GWAS of 462,690...
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