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Article

Development of alveolar and airway cells from human iPS cells: toward SARS-CoV-2 research and drug toxicity testing.

The Journal of toxicological sciences - 1 Jan 2021

Tsuji Kayoko, Yamada Shigeru, Hirai Kazuya, Asakura Hiroshi, Kanda Yasunari

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). SARS-CoV-2 enters host cells by binding with the receptor angiotensin-converting enzyme 2 (ACE2). While ACE2 is expressed in multiple cell types, it has been implicated in the clinical progression of COVID-19 as an entry point for SARS-CoV-2 into respiratory cells. Human respiratory cells, such as airway and...

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Identifiers

PMID: 34470994
DOI: 10.2131/jts.46.425

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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