Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pyroptosis, metabolism, and tumor immune microenvironment

1 Aug 2021

Abstract excerpt

In response to a wide range of stimulations, host cells activate pyroptosis, a kind of inflammatory cell death which is provoked by the cytosolic sensing of danger signals and pathogen infection. In manipulating the cleavage of gasdermins (GSDMs), researchers have found that GSDM proteins serve as the real executors and the deterministic players in fate decisions of pyroptotic cells. Whether inflammatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gout, Hyperuricemia, Uric Acid
Share to Heme Oxygenase-1 and Carbon Monoxide
Share to Inflammasome and immune disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34459122
DOI: 10.1002/ctm2.492

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pyroptosis, metabolism, and tumor immune microenvironmentPMID 34459122Read ↗

The role of pyroptosis in inflammatory diseasesSemantic proximity Read ↗

Mechanism and regulation of pyroptosis-mediated in cancer cell deathSemantic proximity Read ↗

Pyroptosis, inflammasome, and gasdermins in tumor immunitySemantic proximity Read ↗

Pyroptosis as a double-edged sword: The pathogenic and therapeutic roles in inflammatory diseases and cancersSemantic proximity Read ↗

Gasdermin E: A Prospective Target for Therapy of DiseasesSemantic proximity Read ↗

The regulation of pyroptosis by post-translational modifications: molecular mechanisms and therapeutic targetsSemantic proximity Read ↗

Biological Functions of Gasdermins in Cancer: From Molecular Mechanisms to Therapeutic PotentialSemantic proximity Read ↗

Role of Pyroptosis in Gynecological Oncology and Its Therapeutic RegulationSemantic proximity Read ↗

Targeting pyroptosis for cancer immunotherapy: mechanistic insights and clinical perspectivesSemantic proximity Read ↗

Pyroptosis relates to tumor microenvironment remodeling and prognosis: A pan-cancer perspectiveSemantic proximity Read ↗

Pyroptosis and gasdermins—Emerging insights and therapeutic opportunities in metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

Gasdermins and their role in immunity and inflammationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.