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RP11-616M22.7 recapitulates imatinib resistance in gastrointestinal stromal tumor

29 May 2021

Abstract excerpt

Emerging evidence has shown that long non-coding RNAs (lncRNAs) play crucial roles in human cancers. However, systematic characterization of lncRNAs and their roles in gastrointestinal stromal tumor (GIST) therapy have been lacking. We performed high-throughput RNA sequencing (RNA-seq) of 20 GIST and paired adjacent normal samples. We characterized the transcriptional landscape and dysregulation of lncRNAs in...

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PMID: 34458010
DOI: 10.1016/j.omtn.2021.05.017

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