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Article

Topoisomerase II is regulated by translationally controlled tumor protein for cell survival during organ growth in Drosophila.

Cell death & disease - 27 Aug 2021

Yang Dae-Wook, Mok Jung-Wan, Telerman Stephanie B, Amson Robert, Telerman Adam, Choi Kwang-Wook

Abstract excerpt

Regulation of cell survival is critical for organ development. Translationally controlled tumor protein (TCTP) is a conserved protein family implicated in the control of cell survival during normal development and tumorigenesis. Previously, we have identified a human Topoisomerase II (TOP2) as a TCTP partner, but its role in vivo has been unknown. To determine the significance of this interaction, we examined...

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Identifiers

PMID: 34453033
DOI: 10.1038/s41419-021-04091-y
PMCID: PMC8397738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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