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Article

Transcriptional Comparison of Human and Murine Retinal Neovascularization

28 Dec 2023

Abstract excerpt

Purpose: Retinal neovascularization (RNV) is the leading cause of vision loss in diseases like proliferative diabetic retinopathy (PDR). A significant failure rate of current treatments indicates the need for novel treatment targets. Animal models are crucial in this process, but current diabetic retinopathy models do not develop RNV. Although the nondiabetic oxygen-induced retinopathy (OIR) mouse model is used...

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PMID: 38153746
DOI: 10.1167/iovs.64.15.46

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