Article
Genome-wide analyses of Mycobacterium tuberculosis complex isolates reveal insights into circulating lineages and drug resistance mutations in The Gambia.
Scientific reports - 4 Mar 2026
Faal Fatou, Top Naffie, Jobe Olimatou, Colley Sang M, Ayorinde Abigail, Mendy Alieu, Sarr-Kuyateh Binta, Donkor Simon, Antonio Martin, de Jong Bouke C, Rachow Andrea, Kampmann Beate, Sutherland Jayne S, Li Hongwei, Blundell Tom L, Campino Susana, Kohl Thomas, Dreyer Viola, Neimann Stefan, Pandurangan Arun P, Clark Taane G, Phelan Jody E, Tientcheu Leopold D
Abstract excerpt
Tuberculosis (TB), caused by the Mycobacterium tuberculosis complex (MTBC), remains a pressing global health challenge, with a high burden in West Africa, including The Gambia. Understanding the genetic diversity of circulating MTBC strains is essential for improving diagnosis, surveillance and treatment strategies. In this study, we characterise the population structure and drug resistance landscape of MTBC...
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