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Reference set of Mycobacterium tuberculosis clinical strains: A tool for research and product development

25 Mar 2019

Abstract excerpt

The Mycobacterium tuberculosis complex (MTBC) causes tuberculosis (TB) in humans and various other mammals. The human-adapted members of the MTBC comprise seven phylogenetic lineages that differ in their geographical distribution. There is growing evidence that this phylogeographic diversity modulates the outcome of TB infection and disease. For decades, TB research and development has focused on the two...

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PMID: 30908506
DOI: 10.1371/journal.pone.0214088

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