Article
Preexisting Bipolar Disorder Influences the Subsequent Phenotype of Parkinson's Disease.
Movement disorders : official journal of the Movement Disorder Society - 1 Dec 2021
Onofrj Marco, Di Iorio Angelo, Carrarini Claudia, Russo Mirella, Franciotti Raffaella, Espay Alberto J, Boylan Laura S, Taylor John-Paul, Di Giannantonio Massimo, Martinotti Giovanni, Valente Enza M, Thomas Astrid, Bonanni Laura, Delli Pizzi Stefano, Dono Fedele, Sensi StefanoL
Abstract excerpt
BACKGROUND: Patients with bipolar spectrum disorders (BSDs) exhibit an increased risk of Parkinson's disease (PD). OBJECTIVE: The aim is to investigate whether a previous diagnosis of BSDs influences the phenotype of PD. METHODS: Of 2660 PD patients followed for at least 6 years (6-27), 250 (BSD-PD) had BSDs, 6-20 years before PD diagnosis; 48%-43% had a PD or BSD family history, and 34 carried glucocerebrosidase...
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