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Article

A novel germline BRCA2 mutation in a Chinese patient with prostate cancer sensitive to platinum chemotherapy: a case report.

BMC urology - 23 Aug 2021

Jiang Lijuan, Bai Zunguang, Zhu Shoulun, Zhao Tingting, Yang Yining, Li Zhiyong, Chen Dong, Wu Zhiming, Wang Yanjun, Zhou Fangjian, Li Yonghong

Abstract excerpt

BACKGROUND: Germline BRCA2 mutation is associated with an aggressive prostate cancer phenotype and indicates higher risk for hereditary cancer. Recently, numerous studies have attempted to identify the genomic landscape of prostate cancer to better understand the genomic drivers of this disease and look for the molecular targets to guide treatment selection. CASE PRESENTATION: We report a 67-year-old patient...

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Identifiers

PMID: 34425813
DOI: 10.1186/s12894-021-00879-4
PMCID: PMC8381549

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