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Elevated levels of circulating mitochondrial DNA predict early allograft dysfunction in patients following liver transplantation

23 Aug 2021

Abstract excerpt

BACKGROUND AND AIM: The role of circulating mitochondrial DNA (cmtDNA) in transplantation remains to be elucidated. cmtDNA may be released into the circulation as a consequence of liver injury; yet recent work also suggests a causative role for cmtDNA leading to hepatocellular injury. We hypothesized that elevated cmtDNA would be associated with adverse events after liver transplantation (LT) and conducted an...

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PMID: 34425021
DOI: 10.1111/jgh.15670

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