Article
IL27 T4730C Polymorphism and Serology in Multiple Sclerosis: A Pilot Study.
In vivo (Athens, Greece) - 1 Jan 2000
Barac Ioana S, Văcăraș Vitalie, Cozma Angela, Văleanu Mădălina, Decea Nicoleta, Mureșanu Dafin F, Procopciuc Lucia M
Abstract excerpt
BACKGROUND: Multiple sclerosis (MS) is one of the most debilitating neurological diseases of young adults. The presence of a single nucleotide polymorphism in the promoter regions of the interleukin 27 gene (IL27 T4730C, rs181206) may alter the transcription and the production of cytokine levels, leading to MS. PATIENTS AND METHODS: We performed a case-control study including 82 individuals: 51 patients diagnosed...
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