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Article

IL‐20 is involved in obesity by modulation of adipogenesis and macrophage dysregulation

17 Aug 2021

Abstract excerpt

IL-20 is a proinflammatory cytokine of the IL-10 family and involved in several diseases. However, the regulatory role of IL-20 in obesity is not well understood. We explored the function of IL-20 in the pathogenesis of obesity-induced insulin resistance by ELISA, Western blotting and flow cytometry. The therapeutic potential of IL-20 monoclonal antibody 7E for ameliorating diet-induced obesity was analysed in...

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PMID: 34403503
DOI: 10.1111/imm.13403

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