Article
Host-dependent editing of SARS-CoV-2 in COVID-19 patients.
Emerging microbes & infections - 1 Dec 2021
Gregori Josep, Cortese Maria Francesca, Piñana Maria, Campos Carolina, Garcia-Cehic Damir, Andrés Cristina, Abril Josep Francesc, Codina Maria Gema, Rando Ariadna, Esperalba Juliana, Sulleiro Elena, Joseph Joan, Saubí Narcís, Colomer-Castell Sergi, Martin Mari Carmen, Castillo Carla, Esteban Juan Ignacio, Pumarola Tomas, Rodriguez-Frias Francisco, Antón Andrés, Quer Josep
Abstract excerpt
A common trait among RNA viruses is their high capability to acquire genetic variability due to viral and host mechanisms. Next-generation sequencing (NGS) analysis enables the deep study of the viral quasispecies in samples from infected individuals. In this study, the viral quasispecies complexity and single nucleotide polymorphisms of the SARS-CoV-2 spike gene of coronavirus disease 2019 (COVID-19) patients...
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