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Article

Transformation of non-small cell lung cancer into small cell lung cancer in a patient with advanced lung cancer: a case report.

The Journal of international medical research - 1 Aug 2021

Yang Zhengyuan, Lin Yingcheng, Wang Hongbiao

Abstract excerpt

Targeted therapy in patients with epidermal growth factor receptor (EGFR)-mutated non-small cell lung cancer (NSCLC) often fails because of drug resistance. Here, we report a 57-year-old male patient with stage IV small cell lung cancer (SCLC) transformation during targeted therapy. Chest computerized tomography (CT), hematoxylin and eosin histological examination, immunohistochemistry, allele refractory mutation...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 34396834
DOI: 10.1177/03000605211035005
PMCID: PMC8371742

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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