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Human Endothelial Cell Spheroid-based Sprouting Angiogenesis Assay in Collagen

1 Jan 2018

Abstract excerpt

Angiogenesis, the formation of new blood vessels from pre-existing ones plays an important role during organ development, regeneration and tumor progression. The spheroid-based sprouting assay is a well-established and robust method to study the influence of genetic alterations or pharmacological compounds on capillary-like tube formation of primary cultured endothelial cells. A major advantage of this assay is...

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PMID: 34395793
DOI: 10.21769/bioprotoc.2995

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