Article
Increased myofiber remodelling and NFATc1-myonuclear translocation in rat postural skeletal muscle after experimental vestibular deafferentation.
Journal of vestibular research : equilibrium & orientation - 1 Jan 2013
Luxa Nicholas, Salanova Michele, Schiffl Gudrun, Gutsmann Martina, Besnard Stéphane, Denise Pierre, Clarke Andrew, Blottner Dieter
Abstract excerpt
BACKGROUND: The vestibular system undergoes considerable modification during spaceflight [5]. This is paralleled by microgravity-induced muscle atrophy [6]. However, the possibility of vestibulo-autonomic regulatory mechanisms affecting skeletal muscle structure and function have not yet been addressed. OBJECTIVE: We hypothesise that the vestibular system affects anti-gravitational skeletal muscle phenotype...
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