Article
A cross-level information transmission network for hierarchical omics data integration and phenotype prediction from a new genotype.
Bioinformatics (Oxford, England) - 22 Dec 2021
He Di, Xie Lei
Abstract excerpt
MOTIVATION: An unsolved fundamental problem in biology is to predict phenotypes from a new genotype under environmental perturbations. The emergence of multiple omics data provides new opportunities but imposes great challenges in the predictive modeling of genotype-phenotype associations. Firstly, the high-dimensionality of genomics data and the lack of coherent labeled data often make the existing supervised...
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