Article
CLCLSA: Cross-omics linked embedding with contrastive learning and self attention for integration with incomplete multi-omics data.
Computers in biology and medicine - 1 Mar 2024
Zhao Chen, Liu Anqi, Zhang Xiao, Cao Xuewei, Ding Zhengming, Sha Qiuying, Shen Hui, Deng Hong-Wen, Zhou Weihua
Abstract excerpt
Integration of heterogeneous and high-dimensional multi-omics data is becoming increasingly important in understanding etiology of complex genetic diseases. Each omics technique only provides a limited view of the underlying biological process and integrating heterogeneous omics layers simultaneously would lead to a more comprehensive and detailed understanding of diseases and phenotypes. However, one obstacle...
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