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Slc44a2 deletion alters tetraspanin and N-cadherin expression: Reduced adhesion and enhanced proliferation in cultured mesenchymal lung cells.

Tissue & cell - 1 Dec 2021

Nair Thankam S, Kakaraparthi Bala Naveen, Yang Lucy, Lu Lillian, Thomas Trey B, Morris Anna C, Kommareddi Pavan, Kanicki Ariane, Carey Thomas E

Abstract excerpt

Slc44a2 is reported to interact with tetraspanins CD9 and CD81. To investigate how Slc44a2 affects adhesion protein expression, cells from wild-type (WT) Slc44a2+/+, heterozygous (HET) Slc44a2+/-, and knockout (KO) Slc44a2-/- mice were cultured from lung tissue. The cultured cells expressed vimentin, N-cadherin, p120 catenin, beta-catenin, actin, CD9, and CD81, but not E-cadherin. Vimentin expression with lack of...

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Identifiers

PMID: 34371293
DOI: 10.1016/j.tice.2021.101599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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