Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

PSMB7 Is a Key Gene Involved in the Development of Multiple Myeloma and Resistance to Bortezomib

23 Jul 2021

Abstract excerpt

Multiple myeloma (MM), the second most commonly diagnosed hematologic neoplasm, is the most significant clinical manifestation in a series of plasma cell (PC) dyscrasia. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering MM (SMM), approximately 1% or 10% of which, respectively, can progress to MM per year, are the premalignant stages of MM. The overall survival (OS) of MM is significantly...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Multiple Myeloma Research and Treatments
Share to Protein Degradation and Inhibitors
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34367968
DOI: 10.3389/fonc.2021.684232

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

PSMB7 Is a Key Gene Involved in the Development of Multiple Myeloma and Resistance to BortezomibPMID 34367968Read ↗

Exploring the Molecular Mechanisms and Shared Genetic Characteristics of Monoclonal Gammopathy of Undetermined Significance and Multiple MyelomaSemantic proximity Read ↗

Single-cell sequencing analysis of multiple myeloma heterogeneity and identification of new theranostic targetsSemantic proximity Read ↗

Integrative Analysis of Bulk RNA-Seq and Single-Cell RNA-Seq Unveils Novel Prognostic Biomarkers in Multiple MyelomaSemantic proximity Read ↗

Single-cell sequencing analysis of multiple myeloma heterogeneity and identification of new theranostic targetsSemantic proximity Read ↗

Identification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verificationSemantic proximity Read ↗

Mitophagy-related gene signature for predicting the prognosis of multiple myelomaSemantic proximity Read ↗

A Comprehensive Targeted Panel of 295 Genes: Unveiling Key Disease Initiating and Transformative Biomarkers in Multiple MyelomaSemantic proximity Read ↗

Integrating plasma proteomes with genome-wide association data for causal protein identification in multiple myeloma.Semantic proximity Read ↗

Identification and validation of SSBP1 as a key regulator involved in the development of multiple myeloma via p38MAPK signaling pathwaySemantic proximity Read ↗

CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagySemantic proximity Read ↗

Single cell RNA-seq data and bulk gene profiles reveal a novel signature of disease progression in multiple myelomaSemantic proximity Read ↗

Comprehensive analysis of PSMD family members and validation of PSMD9 as a potential therapeutic target in human glioblastomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.