Article
Vitamin D receptor gene polymorphism TaqI (rs731236) and its association with the susceptibility to coronary artery disease among Pakistani population.
The journal of gene medicine - 1 Dec 2021
Kulsoom Ume, Khan Amber, Saghir Tahir, Nawab Syeda Nuzhat, Tabassum Atiya, Fatima Sehrish, Saleem Saima, Zehra Sitwat
Abstract excerpt
BACKGROUND: Coronary artery disease (CAD) is a leading cause of mortality in Pakistan and also worldwide. Vitamin D receptor (VDR) regulates the transcription of many genes and has a significant impact on inflammation and the morphology of cardiac cells. Genetic variation in the VDR gene such as the TaqI polymorphism (rs731236) may have an impact that causes adverse effects. Accordingly, it is important to...
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