Article
Allelic variations of the vitamin D receptor (VDR) gene are associated with increased risk of coronary artery disease in type 2 diabetics: the DIABHYCAR prospective study.
Diabetes & metabolism - 1 May 2013
Ferrarezi D A F, Bellili-Muñoz N, Dubois-Laforgue D, Cheurfa N, Lamri A, Reis A F, Le Feuvre C, Roussel R, Fumeron F, Timsit J, Marre M, Velho G
Abstract excerpt
AIM: Vitamin D deficiency is associated with coronary artery disease (CAD), and the actions of vitamin D are mediated by binding to a specific nuclear vitamin D receptor (VDR). This study investigated the associations of VDR gene variants with CAD in two cohorts of type 2 diabetes patients. METHODS: A cohort of 3137 subjects from the prospective DIABHYCAR study (CAD incidence: 14.8%; follow-up: 4.4 ± 1.3 years)...
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