Article
[Hematologic Phenotype and Genotype Analysis of Patients with Hemoglobin Variants].
Zhongguo shi yan xue ye xue za zhi - 1 Aug 2021
Wang Ye-Fei, Wu Bei-Ying, Xia Wen-Quan, Chen Ning, Hu Yi-Qun
Abstract excerpt
OBJECTIVE: To study the hematologic and molecular features of 14 patients with hemoglobin (Hb) variants, so as to provide reference data for its laboratory screening. METHODS: A total of 1 029 samples were screened by high performance liquid chromatography (HPLC) on the Bio-Rad VariantⅡHPLC system. GAP-PCR and reverse dot blot (RDB) were used to detect common mutation of α and β globin gene in Chinese. DNA...
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