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[Clinical Significance of Truncated Mutant ΔJBP of TET2 Gene in Patients with Acute Myeloid Leukemia].

Zhongguo shi yan xue ye xue za zhi - 1 Aug 2021

Yang Yu-Chao, Xia Ting, Luo Ming, Guo Wen-Zheng, Zhang Ling-Li, Chen Xiu-Hua, Xu Zhi-Fang, Wang Hong-Wei, Tan Yan-Hong

Abstract excerpt

OBJECTIVE: To the clinical characteristics and prognostic value of the patients with complete deletion of TET_JBP domain (ΔJBP) in TET2 acute myeloid leukemia (AML). METHODS: Next Generation Sequencing technology was used to determine the mutations of 34 AML-related genes (including TET2 gene). The I-TASSER tool was used to predict the tertiary structure of the full-length TET2 protein and TET_JBP structure...

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Identifiers

PMID: 34362476
DOI: 10.19746/j.cnki.issn.1009-2137.2021.04.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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