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Article

Differential Serotonin Uptake Mechanisms at the Human Maternal–Fetal Interface

21 Jul 2021

Abstract excerpt

Serotonin (5-HT) plays an extensive role during pregnancy in regulating both the placental physiology and embryonic/fetal development. The uptake of 5-HT into cells is central to the control of local concentrations of 5-HT near its molecular targets. Here, we investigated the mechanisms of 5-HT uptake into human primary placental cells and cord blood platelets, all isolated immediately after birth. Trophoblasts...

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Share to Maternal Mental Health During Pregnancy and Postpartum
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PMID: 34360573
DOI: 10.3390/ijms22157807

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