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Article

The m6A writers regulated by the IL-6/STAT3 inflammatory pathway facilitate cancer cell stemness in cholangiocarcinoma

1 Jan 2021

Abstract excerpt

Objective: Investigation of the regulatory mechanisms of cell stemness in cholangiocarcinoma (CCA) is essential for developingeffective therapies to improve patient outcomes. The purpose of this study was to investigate the function and regulatory mechanismof m6A modifications in CCA cell stemness. Methods: Interleukin 6 (IL-6) treatment was used to induce an inflammatory response, and loss-of-function studies...

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PMID: 34347395
DOI: 10.20892/j.issn.2095-3941.2020.0661

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