Article
EssC is a specificity determinant for Staphylococcus aureus type VII secretion.
Microbiology (Reading, England) - 1 May 2018
Jäger Franziska, Kneuper Holger, Palmer Tracy
Abstract excerpt
The type VII protein secretion system (T7SS) is found in actinobacteria and firmicutes, and plays important roles in virulence and interbacterial competition. A membrane-bound ATPase protein, EssC in Staphylococcus aureus, lies at the heart of the secretion machinery. The EssC protein from S. aureus strains can be grouped into four variants (EssC1-EssC4) that display sequence variability in the C-terminal region....
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